iMOD-K (PI : Hail Kim, M.D., Ph.D.)
Diabetes affects more than 8% of the population. The iMOD-K(Kim) aims to cure diabetes. In an attempt to find ways to cure diabetes, we are focusing on the two most important cells, hepatocytes and pancreas beta cells which are the first line defense to maintain normal blood glucose levels. The scientific identity of this lab is molecular physiology. We take advantage of molecular biology and mouse genetics as research tools. We are actively collaborating with researchers in the different areas. We are open to anyone who wants to cure diabetes or who can help us to cure diabetes.
1. Regulation of differentiation and proliferation of hepatocytes and beta-cells
2. Regulation of glucose metabolism in hepatocytes and beta-cells
3. Tissue specific regulation of gene expression in hepatocytes and beta-cells
4. Reconstitution of pancreatic islets in vitro
iMOD-S (PI : Jae Myoung Suh, Ph.D.)
Welcome to the iMOD-S(Suh) laboratory! Our research focuses on understanding the processes that are involved in the regulation and execution of metabolism. While we are interested in understanding metabolism from a variety of angles, the lab currently focuses on adipose, muscle, brain and exocrine gland function in normal and pathological states. Our research primarily utilizes mouse models along with various cell and molecular biological tools to address questions in the following areas.
1. PPARgamma-FGF1 axis in adipose tissue remodeling and metabolic flexibility
2. PPARdelta-FGF1 axis in muscle regeneration and aging
3. Brain FGF signaling in nutrient and metabolic responses
4. Adipose secretome analysis by proximity ligation
5. Adipose tissue aging and senescence mechanisms
6. Mechanisms of Tph1 in adipose tissue thermogenesis
7. Mechanisms of ERRgamma in exocrine gland function
8. Discovery of novel pathways involved in CNS injury and repair
9. Adipose tissue dedifferentiation mediated by growth signaling pathways
10. Mechanisms of FGF mediated radiomitigation during intestinal injury
We are seeking talented and motivated students and post-docs to join our research team and inquiries can be made by directly contacting Dr. Jae Myoung Suh at jmsuh@kaist.ac.kr
